Structure-based Drug Design Research Group
Team Leader: Dr Robert van Montfort
Location: Haddow Laboratories, Sutton
Section: Cancer Research UK Cancer Therapeutics Unit
The Structure-based Drug Design team is a joint initiative between the Sections of Structural Biology and Cancer Therapeutics and is focused on the structure-based design of novel drugs for the treatment of cancer. We use a combination of high-throughput X-ray crystallography, in silico medicinal chemistry and biophysical methods to probe protein-ligand interactions throughout the hit-generation, hit validation and lead optimisation phases of drug discovery projects at the ICR.
The multidisciplinary team includes protein biochemists, in silico medicinal chemists and protein crystallographers and has strong links with the Medicinal Chemistry from the Section of Cancer Therapeutics as well as teams within the ICR's Section of Structural Biology.
In the Cancer Research UK Cancer Therapeutics Unit
