Radical Chemistry in Heterocyclic Synthesis
Medicinal Chemistry Team Three
Section: Section of Cancer Therapeutics (including the Cancer Research UK Centre for Cancer Therapeutics)
For a number of years, we have been at the forefront of the development of radical chemistry to make heterocyclic compounds of biological interest. Currently, we are using radicals in a remote activation sequence to generate the tetracyclic mitosene core in a short and stereo-controlled manner. This chemistry should allow the rapid synthesis of heterocyclic systems from simple substrates lacking conventional functionality.
In the Section of Cancer Therapeutics (including the Cancer Research UK Centre for Cancer Therapeutics)
